Cempedak leaf extract (Artocarpus champeden) as a novel ingredient in antibacterial peel-off gel face masks

Faizah Alivia Putri; Widia Widia; Syarmila Syarmila; Robby Gus Mahardika

doi:10.20884/1.api.2022.10.2.4920

Faizah Alivia Putri Department of Chemistry, Universitas Bangka Belitung, Bangka Regency 33172, Indonesia.
Widia Widia Department of Chemistry, Universitas Bangka Belitung, Bangka Regency 33172, Indonesia.
Syarmila Syarmila Department of Chemistry, Universitas Bangka Belitung, Bangka Regency 33172, Indonesia.
Robby Gus Mahardika Department of Chemistry, Universitas Bangka Belitung, Bangka Regency 33172, Indonesia. http://orcid.org/0000-0002-5569-9459

DOI: https://doi.org/10.20884/1.api.2022.10.2.4920

Abstract

Background: Phenolic compounds in plants act as natural antioxidants, with cempedak (Artocarpus champeden) leaf extract showing promise due to its high phenolic content and potential antibacterial properties against Propionibacterium acnes.

Objective: This study explores the effectiveness of cempedak leaf extract as an active ingredient in peel-off gel face masks for antibacterial purposes.

Methods: Cempedak leaf extract was analyzed for phenolic content and Fourier transform infrared (FTIR). Its antibacterial activity was tested against P. acnes using agar diffusion, comparing inhibition zones with positive control. A peel-off gel face mask was formulated with cempedak leaf extract, undergoing physical and an irritation test.

Results: Cempedak leaf extract contained a total phenolic content of 342.35 mg EAG/g and exhibited significant antibacterial activity. The face mask formulation with cempedak leaf extract showed promising physical properties and did not irritate, meeting the peel-off gel face mask standards.

Conclusion: Cempedak leaf extract has potent antibacterial properties, making it an effective ingredient in peel-off gel face masks for treating acne. Further research could explore its commercial potential in skincare products.