Identifikasi Serotipe dan Sensitivitas Antibiotik S. pneumoniae yang Dibawa Nasofaring Penderita Oma di Kabupaten Banyumas
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https://doi.org/10.20884/1.bioe.2020.2.1.1779
Abstrak
Tujuan penelitian ini untuk mendeteksi S. pneumoniae yang dibawa oleh nasofaring anak-anak penderita OMA usia sekolah dasar (6-12 tahun). Desain penelitian ini adalah penelitian survei noneksperimental dengan metode analisis deskriptif. Pengambilan sampel dilakukan pada bulan September 2018 hingga Desember 2018 di SD Kabupaten Banyumas. Deteksi S. pneumoniae pada sampel OMA dapat dilakukan melalui metode identifikasi S. pneumoniae secara mikrobiologi. Hasil penelitian ini menunjukkan bahwa jumlah S. pneumoniae yang dibawa oleh nasofaring anak-anak penderita OMA di wilayah kabupaten Banyumas adalah sebanyak 9 dari 26 sampel OMA.
Referensi
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Hadinegoro, S.R., Prayitno, A., Khoer, M. M., Djelantik, I. G. G., Dewi, N. E., Indriyani, A. K., Muttaqin, Z., Safari, D. 2016. Nasopharyngeal carriage of Streptococcus pneumoniae in healthy children under five years old in central lombok regency, Indonesia. Southeast Asian J Trop Med Public Health, 3(3): 1-9.
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Keller, L. E., D. A. Robinson, L. S. McDaniel, L. S. 2016. Nonecapsulated Streptococcus pneumoniae: emergence and pathogenesis. American Society for Microbiology, 7(2): 1-12.
Korona-Glowniak, I., Zychowski, P., Siwiec, R., Mazur, E., Niedxielska, G., Malm, A. 2018. Resistant Streptococcus pneumoniae strains in children with acute otitis media-high risk of persistent colonization after treatment. BMC Infectious Disease, 18: 1-12.
Nonmark-Henriques, B., Toumanen, E. I., 2013. The pneumococcus: Epidemiology microbiology, and pathogenesis. Cold Spring Harb Perspect Med, 3:a010215.
Pikis, A., Campos, J. M., Rodriguez, W. J., Keith, J. M. 2001. Optochin resistance in Streptococcus pneumoniae: Mechanism, significance, and clinical implications. The Journal of Infectious Disease, 184: 582-590.
Pinti, M., Appay, V., Campisi, J., Frasca, D., Fulop, T., Sauce, D., Larbi, A., Weinberg, B., Cossarizza, A. 2016. Aging of the immune system-focus on inflammation and vaccination. European Journal of Immunology, 46: 2286–2301.
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Tam, S. S., Lee, C., Winter, R.E. 1993. Hemin utilization is related to virulence of Streptococcus
pneumoniae. American Society for Microbiology. 61(12): 5401-5405.
Auranen, K., Rinta-Kokko, H., Goldblatt, D., Nohynek H., O'Brien, K. L. 2013. Colonisation endpoints in Streptococcus pneumoniae vaccine trials. Vaccine, 32: 153-158.
Bogaert, D., De Groot, R., Hermans, P. W. M. 2004. Strep¬tococcus pneumoniae colonisation: the key to pneumococcal disease. Lancet Infect Dis, 4: 144-1454.
Bosch, A. A., Biesbroek, G., Trzcinski, K., Sanders, E. A., Bogaert, D. 2013. Viral and bacterial interactions in the upper respiratory tract. PLoS Pathog, 9:e1003057.
Bridy-Pappas, A. E., Pharm, D., Margolis, M. B., Pharm, D., Center, K. J. M. D., Isaacman, D. J. M D. 2005. Streptococcus pneumoniae: Description of the pathogen disease epidemiology, treatment, and prevention. Pharmacotherapy, 25(9): 1193-1212.
Carvalho, M. D. G., Pimenta, F. C., Jackson, D., Roundtree, A., Ahmad, Y., Millar, E. V., Beall, B. W. 2010. Revisiting pneumococcal carriage by use of broth enrichment and PCR techniques for enhanced detection of carriage and serotypes. Journal of clinical microbiology, 48(5): 1611-1618.
CDC. 2015. Epidemiology and prevention of vaccine-preventable disease: Pneumococcal disease. USA: Centers for Disease Control and Prevention.
Dunne, E. M., Lupiwa, T., Montgomery, J. 2010. Streptococcus pneumoniae serogroups and colony morphology: a look back. Papua New Guinea Medical Journal, 53: 166-168.
Farida, H., Severin, J. A., Gasem M. H., Keuter, M., Wahyono, H.. 2014. Nasopharyngeal carriage of Streptococcus pneumoniae-prone age groups in Semarang, Java Island, Indonesia. PLoS ONE, 9.
Ferrandiz, M. J., De la Campa, A. G. 2002. The membrane-assosiated F0F1 ATPase is essential for the viability of Streptococcus pneumoniae. FEMS Microbiology Letters, 212: 133-138.
Hadinegoro, S.R., Prayitno, A., Khoer, M. M., Djelantik, I. G. G., Dewi, N. E., Indriyani, A. K., Muttaqin, Z., Safari, D. 2016. Nasopharyngeal carriage of Streptococcus pneumoniae in healthy children under five years old in central lombok regency, Indonesia. Southeast Asian J Trop Med Public Health, 3(3): 1-9.
Kadioglu, A., Weiser, J. N., Paton, J. C., Andrew, P. W. 2008. The Role of Streptococcus pneumoniae: Emergence and pathogenesis. mBio, 7(2): 1792-1815.
Keller, L. E., D. A. Robinson, L. S. McDaniel, L. S. 2016. Nonecapsulated Streptococcus pneumoniae: emergence and pathogenesis. American Society for Microbiology, 7(2): 1-12.
Korona-Glowniak, I., Zychowski, P., Siwiec, R., Mazur, E., Niedxielska, G., Malm, A. 2018. Resistant Streptococcus pneumoniae strains in children with acute otitis media-high risk of persistent colonization after treatment. BMC Infectious Disease, 18: 1-12.
Nonmark-Henriques, B., Toumanen, E. I., 2013. The pneumococcus: Epidemiology microbiology, and pathogenesis. Cold Spring Harb Perspect Med, 3:a010215.
Pikis, A., Campos, J. M., Rodriguez, W. J., Keith, J. M. 2001. Optochin resistance in Streptococcus pneumoniae: Mechanism, significance, and clinical implications. The Journal of Infectious Disease, 184: 582-590.
Pinti, M., Appay, V., Campisi, J., Frasca, D., Fulop, T., Sauce, D., Larbi, A., Weinberg, B., Cossarizza, A. 2016. Aging of the immune system-focus on inflammation and vaccination. European Journal of Immunology, 46: 2286–2301.
Satzke, C., Turner, P., Virolainen-Julkunen, A., Adrian, P. V., Antonio, M. 2013. Standard method for detecting uppers respiratory carriage of Streptococcus pneumoniae: Updated recommendations from the world health organization pneumococcal carriage working group. J. Vaccine, 32: 165-179.
Tam, S. S., Lee, C., Winter, R.E. 1993. Hemin utilization is related to virulence of Streptococcus
pneumoniae. American Society for Microbiology. 61(12): 5401-5405.
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2020-04-29
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OVIANI, Miranti; WAHYONO, Daniel Joko; SAFARI, Dodi.
Identifikasi Serotipe dan Sensitivitas Antibiotik S. pneumoniae yang Dibawa Nasofaring Penderita Oma di Kabupaten Banyumas.
BioEksakta : Jurnal Ilmiah Biologi Unsoed, [S.l.], v. 2, n. 1, p. 11-15, apr. 2020.
ISSN 2714-8564.
Tersedia pada: <https://jos.unsoed.ac.id/index.php/bioe/article/view/1779>. Tanggal Akses: 07 sep. 2025
doi: https://doi.org/10.20884/1.bioe.2020.2.1.1779.
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