Identifikasi Serotipe dan Sensitivitas Antibiotik S. pneumoniae yang Dibawa Nasofaring Penderita Oma di Kabupaten Banyumas

  • Miranti Oviani Mahasiswi Biologi Unsoed
  • Daniel Joko Wahyono Univeristas Jenderal Soedirman
  • Dodi Safari Univeristas Jenderal Soedirman

Abstract

The aims of this study are to detect S. pneumoniae carried by nasopharnyx of children in primary school (aged 6-12 years) that diagnosed with AOM, to identify sensitivity of S. pneumoniae to antibiotics. The design of this study is nonexperimental survey with the descriptive analysis. Sampling was conducted in September - December 2018 in Banyumas district primary schools. Detection of S. pneumoniae was performed with microbiology methods. Meanwhile, serotype was determined by multiplex PCR and sensitivity to antibiotics was deduced using disc diffusion.


The result of this study showed that carriage rate of S. pneumoniae carried by nasopharynx in children aged over 5 years that diagnosed with AOM in the Banyumas district was 35%. Serotype of S. pneumoniae obtainend from this study were 6A/6B, 6C/6D, 17F, 3, 13, 14, 23B, and untypeable. In addition, isolates of S. pneumoniae were highly susceptible to clindamycin (100%), erythromycin (100%), sulphametaxazole/trimethoprim (100%), chloramphenicol (88%), oxacillin (77%), and tetracycline (66%).


 

Published
2020-04-29
How to Cite
OVIANI, Miranti; WAHYONO, Daniel Joko; SAFARI, Dodi. Identifikasi Serotipe dan Sensitivitas Antibiotik S. pneumoniae yang Dibawa Nasofaring Penderita Oma di Kabupaten Banyumas. BioEksakta, [S.l.], v. 2, n. 1, p. 11-15, apr. 2020. ISSN 2714-8564. Available at: <http://jos.unsoed.ac.id/index.php/bioe/article/view/1779>. Date accessed: 15 july 2020. doi: https://doi.org/10.20884/1.bioe.2020.2.1.1779.