ANALYSIS OF THE IMPACT OF TRANSVERSUS ABDOMINIS PLANE BLOCK AND INTRATHECAL MORPHINE AS POST-CESAREAN

  • Bambang Sulistyo Department of Anesthesiology, Dirgahayu Hospital, Samarinda, Indonesia
  • Wisnu Budi Pramono Department of Anesthesiology, Faculty of Medicine, Jenderal Soedirman University, Purwokerto
  • Wahyudin Wahyudin Department of Pharmacology, Faculty of Medicine, Jenderal Soedirman University, Purwokerto

Abstract

Background: Surgical wound pain 24 hours after cesarean section is still a problem found in obstetric patients. Many drugs are used to reduce pain scores both orally, intravenously, transdermally and others. However, it is necessary to pay attention to the dosage of the drug so that it does not harm the postoperative patient. Other methods that can be used include preoperative administration of intrathecal morphine and administration of transversus abdominis muscle blocks. Methods :The study's experimental design uses a post-test only control group. Three groups were created from 108 cesarean patients who had no problems. As per standard protocol, the control group (K) had a cesarean section with intravenous analgesia after the procedure. The Intrathecal Morphine (M) group got preoperative intrathecal morphine in addition to the same treatment as the K group. Apart from receiving the same treatment as group K, the Transversus Abdominis Plane Block (B) group also underwent bilateral transversus abdominis muscle blocks guided by ultrasonography. SPSS for Windows Release 26.0 was used to process the data, and differences with a significance level of 0.05 were examined using the One-Way ANOVA test analysis and the Bonferroni Post Hoc test. Outcomes: Group B differed significantly from group K on the visual analogue scale (p value = 0.000). Similar results were obtained for Group M compared to Group K (p value = 0.000). Group B and group M differ significantly from one another, as can be shown, Compared to group M, group B's visual analogue scale is lower (p=0.000). Conclusion: Intrathecal morphine and transversus abdominis block are effective in reducing post-cesarean section pain. Obtained a lower pain score in the administration of transversus abdominis block compared to intrathecal morphine with a significant difference.

References

Ban MinGi, Choi Yong Seon, Koo Bon-Nyeo. Analgesic Effect of Intrathecal Morphine Combined with Low Dose Bupivacaine on Postoperative Analgesia after Liver Resection: A Randomized Controlled Study. Journal of Personalized Medicine 2022;12:211.
Butterworth John, Mackey David, Wasnick John D. Morgan and Mikhail’s Clinical Anaesthesiology 6th ed 2018: 981.
Cosgrave David, Shanahan Enda, Conlon Niamnh, Joshi Muralidhar (ed). Intrathecal Opioids. World Federation of Societies of Anaesthesiologist 2017 February 21st ;347:1-6. 77
Cummings Adrienne, Orgill D Britlyn, Fitzgerald Brian M. Intrathecal Morphine. PubMed 2022 May 1 [ cited 2022 June 13] :1-7
Eko Nofiyanto, Ristiawan Muji Laksono, Isngadi. Transversus Abdominis Plane Block as Postoperative Analgesic for Caesarian Section Patients with Severe Mitral Stenosis. Journal of Anaesthesia and Pain 2020;1(2):38-43.
Escudero-Fung Maria, Lehman Erik B, Karamchandani Kunal. Timing of Transversus Abdominis Plane Block and Postoperative Pain Management. Local and Regional Anesthesia 2020;13:185-193.
Girgin Nermin, Gulbert Alp, Turker Gurkan, et al. Intrathecal Morphine in Anesthesia for Caesarian Delivery: Dose Response Relationship for Combinations of Low Dose Intrathecal Morphine and Spinal Bupivacaine. Journal of Clinical Anesthesia 2008 May:180-5.
Liu Lin, Xie Yan-Hu, Zhang Wei, et al. Effect of Transversus Abdominis Plane Block on Postoperative Pain after Colorectal Surgery: A Meta-Analysis of Randomized Controlled Trials. Med Princ Pract 2018;27:158-165.
Rahimzadeh Poupak, Hamid Sayed RF, Lativi Kaveh, et al. A Comparison of Effect of Preemptive Versus Post Operative Use of Ultrasound-Guided Bilateral Transversus Abdominis Plane (TAP) Block on Pain Relief After Laparoscopic Cholesystectomy. Scientific Reports 2022;12:623.
Sato Izumi, Iwasaki Hajime, Luthe Sarah Kyuragi, et al. Comparison of Intathecal Morphine with Continuous Patient Controlled Epidural Anesthesia Versus Inthathecal Morphine Alone for Post-Caesarean Section Analgesia : A Randomized Controlled Trial. BMC Anesthesiology 2020;20:138.
Sultan Pervez, Halpern StephenH, Pushpanathan Ellile, et al. The Effect of Inthathecal Morphine Dose on Outcomes after Elective Caesarian Delivery : A Meta-Analysis. International Anesthesia Research Society 2016;123(1):154-64.
Wiisanen Michael T, Raghavendra Meda. Transversus Abdominis Block. PubMed 2018 May 31 [cited 2022 June 13] : 1-5.
Zhao Yi, Yan Jing, Chen Xiang Dong. Transversus Abdominis Plane Block for Postoperative Pain Relief after Abdominal Surgery. Journal of Anesthesia and Perioperative Medicine 2018;5:242-6
Published
2026-03-31
How to Cite
SULISTYO, Bambang; PRAMONO, Wisnu Budi; WAHYUDIN, Wahyudin. ANALYSIS OF THE IMPACT OF TRANSVERSUS ABDOMINIS PLANE BLOCK AND INTRATHECAL MORPHINE AS POST-CESAREAN. Mandala Of Health, [S.l.], v. 19, n. 1, p. 71-78, mar. 2026. ISSN 2615-6954. Available at: <https://jos.unsoed.ac.id/index.php/mandala/article/view/17755>. Date accessed: 01 apr. 2026. doi: https://doi.org/10.20884/1.mandala.2026.19.1.17755.