HUBUNGAN KADAR NATRIUM DAN KALIUM SERUM DENGAN TEKANAN DARAH DAN DENYUT NADI PADA PASIEN GAGAL JANTUNG
Abstract
Heart failure is the inability of the heart to carry out its function, namely pumping blood at a normal frequency for tissue needs, which causes compensatory mechanisms, namely activation of the renin-angiotensin system, narrowing of the arteries and release of adrenergic. The renin-angiotensin system will increase renin which will then increase aldosterone, causing changes in serum sodium levels and serum potassium levels. Meanwhile, narrowing of the arteries due to decreased contractility will affect blood pressure, while adrenergic release will increase the pulse rate. This study aims to prove the relationship between serum sodium and potassium levels with blood pressure and pulse rate in heart failure patients. This research is a cross sectional study, with 23 patients as respondents. Samples were collected using the sequential sampling method. The data used are medical records that check serum sodium and potassium levels at one time with blood pressure and pulse. The results obtained showed that the average serum sodium level was 135.7 ± 6.643 mEq/L, the average serum potassium level was 4,087 ± 0.7485 mEq/L, the average systolic blood pressure was 123.35 ± 29.518 mmHg, the average mean diastolic blood pressure 70.43 ± 31,334 mmHg, mean pulse 99 ± 31,010 times per minute. The significance value of the Spearman Rank test on serum sodium levels with blood pressure was 0.910 (p>0.05), on sodium levels with pulse rate was 0.713 (p>0.05), on serum potassium levels with blood pressure was 0.076 (p> 0.05), and serum potassium level with pulse was 0.344 (p>0.05). It can be concluded that there is no significant relationship between serum sodium and potassium levels and blood pressure and pulse rate.
References
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Mende, C. W. and Bloomgarden, Z. T. (2023) ‘Serum sodium as a diabetes risk factor?’, Journal of Diabetes, 15(2), pp. 84–85. doi: 10.1111/1753-0407.13365.
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Saelan, S. and Teguh, S. (2018) ‘Pengaruh pola hidup terhadap perubahan denyut nadi pada pasien heart failure’, Jurnal Kesehatan Kusuma Husada, 00(August 2015), pp. 78–86. doi: 10.34035/jk.v9i1.263.
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Tambuwun, C. F. D., Panda, A. L. and Rampengan, S. H. (2016) ‘Gambaran pasien gagal jantung dengan penyakit hipertensi yang menjalani rawat inap di RSUP Prof. Dr. R. D. Kandou Manado periode September – November 2016’, e-CliniC, 4(2). doi: 10.35790/ecl.4.2.2016.14680.
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Wei, K. Y. et al. (2020) ‘Dietary potassium and the kidney: Lifesaving physiology’, Clinical Kidney Journal, 13(6), pp. 952–968. doi: 10.1093/CKJ/SFAA157.
Wulandari, T., Nurmainah and Robiyanto (2015) ‘Gambaran Penggunaan Obat Pada Pasien Gagal Jantung Kongestif Rawat Inap Di Rumah Sakit Sultan Syarif Mohamad Alkadrie Pontianak’, jurnal Farmasi Kalbar, 3(1), pp. 1–9.
Youssef, G. S. (2022) ‘Salt and hypertension: current views’, e-Journal of Cardiology Practice, 22(February), p. 2022.
Anderson, D. (2016) Harrison’s principles of internal medicine. 16th edn, The McGraw – Hill Companies. 16th edn. doi: 10.1212/01.wnl.0000161672.02235.a0.
Böhm, M. et al. (2020) ‘Optimization of heart failure treatment by heart rate reduction’, International Journal of Heart Failure, 2(1), p. 1. doi: 10.36628/ijhf.2019.0009.
Can, C. et al. (2014) ‘The relationship between serum sodium concentration and atrial fibrillation among adult patients in emergency department settings’, Journal of Academic Emergency Medicine, pp. 131–134. doi: 10.5152/jaem.2014.172.
Charpentier, F. et al. (1993) ‘Early after/depolarizations and triggered activity: mechanisms and autonomic regulation’, Fundamental & Clinical Pharmacology, 7(1), pp. 39–49. doi: 10.1111/j.1472-8206.1993.tb00216.x.
Díez-Villanueva, P. and Alfonso, F. (2016) ‘Heart failure in the elderly’, Journal of Geriatric Cardiology, 13(2), pp. 115–117. doi: 10.11909/j.issn.1671-5411.2016.02.009.
Engka, J. N. A. and Sapulete, I. M. (2016) ‘Hubungan kadar natrium dengan tekanan darah pada remaja di Kecamatan Bolangitang Barat Kabupaten Bolaang Mongondow Utara Rivanli Polii Kandidat Skripsi Fakultas Kedokteran Universitas Sam Ratulangi Manado dipertahankan antara asupan dan menggambarkan peru’, Jurnal e-Biomedik (eBm), 4, p. 7.
Esa Wanodya Nagari, Wieke Sri Wulan, C. K. R. A. (2016) ‘Hubungan antara kadar natrium dengan kadar kalium dalam serum pada diagnosis gagal jantung’, ANALIS KESEHATAN SAINS, 5(1), p. 314. Available at: file:///Users/andreataquez/Downloads/guia-plan-de-mejora-institucional.pdf%0Ahttp://salud.tabasco.gob.mx/content/revista%0Ahttp://www.revistaalad.com/pdfs/Guias_ALAD_11_Nov_2013.pdf%0Ahttp://dx.doi.org/10.15446/revfacmed.v66n3.60060.%0Ahttp://www.cenetec.
Febtrina, R. and Malfasari, E. (2018) ‘Analisa nilai tanda-tanda vital pasien gagal jantung’, Health Care : Jurnal Kesehatan, 7(2), pp. 62–68. doi: 10.36763/healthcare.v7i2.26.
Flannery, G., Gehrig-Mills, R., Billah, B., & Krum, H. (2008) ‘Analysis of randomized controlled trials on the effect of magnitude of heart rate reduction on clinical outcomes in patients with systolic chronic heart failure receiving beta-blockers.’, The American journal of cardiology, 101(6), pp. 865–869. Available at: ???
Gijsbers, L. et al. (2016) ‘Potassium supplementation and heart rate: A meta-analysis of randomized controlled trials’, Nutrition, Metabolism and Cardiovascular Diseases, 26(8), pp. 674–682. doi: 10.1016/j.numecd.2016.05.003.
Hamzah, R. (2017) ‘Hubungan usia dan jenis kelamin dengan kualitas hidup pada penderita gagal jantung di RS PKU Muhamadiyah Yogyakarta’, p. 1. Available at: http://digilib.unisayogya.ac.id/2256/1/NASKAH PUBLIKASI %28RORI HAMZAH%29.pdf.
Jamaluddin and Djafar, Z. (2018) ‘Nilai prognostik hiperglikemia terhadap kejadian gagal jantung pada penderita sindroma koroner akut’, MEDULA: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo, 5(2), pp. 471–477.
JE, H. (2016) Guyton and Hall textbook of medical physiology. Philadelphia: Elsevier.
Kawabata, M. et al. (2015) ‘Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers’, Clinical Pharmacology: Advances and Applications, 7, pp. 29–36. doi: 10.2147/CPAA.S77021.
Kumar, R. (2013) Dasar-dasar patofisiologi penyakit. Volume 1. Jakarta. Penerbit Buku Kedokteran EGC
Lesar, T. S. (2014) ‘Kadar natrium serum pada latihan fisik intensitas ringan mahasiswa fakultas kedokteran Universitas Sam Ratulangi’, Jurnal e-Biomedik, 2(1), pp. 1–6. doi: 10.35790/ebm.2.1.2014.3641.
Lippi, G. and Sanchis-Gomar, F. (2020) ‘Global epidemiology and future trends of heart failure’, AME Medical Journal, 5(Ci), pp. 2–7. doi: 10.21037/amj.2020.03.03.
McNeely JD, Windham BG, and A. DE (2008) ‘Dietary sodium effects on heart rate variability in salt-sensitivity of blood pressure’, Psychophysiology, 23(1), pp. 1–7. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624763/pdf/nihms412728.pdf.
Mende, C. W. and Bloomgarden, Z. T. (2023) ‘Serum sodium as a diabetes risk factor?’, Journal of Diabetes, 15(2), pp. 84–85. doi: 10.1111/1753-0407.13365.
Peng, S. et al. (2023) ‘Relationship between serum sodium levels and all-cause mortality in congestive heart failure patients: A retrospective cohort study based on the Mimic-III database’, Frontiers in Cardiovascular Medicine, 9. doi: 10.3389/fcvm.2022.1082845.
PERKI, K. K. G. J. dan K. (2015) ‘Pedoman tatalaksana gagal jantung’, Perhimpunan Dokter Spesialis Kardiovaskular Indonesia, pp. 848–853.
Rahayu, P. (2021) Hubungan peningkatan tekanan darah dan kontrol hipertensi dengan nilai ejeksi fraksi pada pasien gagal jantung kronik di poli jantung hermina depok tahun 2021.
Regina S. Tulungnen , Ivonny. M. Sapulete, D. H. C. P. (2016) ‘Hubungan kadar natrium dengan tekanan darah pada remaja di kecamatan Bolangitang Barat kabupaten Bolaang Mongondow Utara’, Jurnal Kedokteran Klinik (JKK), 1(2), pp. 37–45. doi: 10.35790/ebm.4.2.2016.14862.
RI Kemenkes (2018) ‘Laporan nasional riskesdas 2018’, Badan Penelitian dan Pengembangan Kesehatan, p. 198. Available at: http://labdata.litbang.kemkes.go.id/images/download/laporan/RKD/2018/Laporan_Nasional_RKD2018_FINAL.pdf
Romanovsky, A., Bagshaw, S. and Rosner, M. H. (2011) ‘Hyponatremia and congestive heart failure: a marker of increased mortality and a target for therapy’, International Journal of Nephrology, 2011, pp. 1–7. doi: 10.4061/2011/732746.
Saelan, S. and Teguh, S. (2018) ‘Pengaruh pola hidup terhadap perubahan denyut nadi pada pasien heart failure’, Jurnal Kesehatan Kusuma Husada, 00(August 2015), pp. 78–86. doi: 10.34035/jk.v9i1.263.
Sari, I. A. (2021) ‘Gambaran kadar natrium pada pasien gagal jantung di RSUD Dr. M. Djamil Padang’, Doctoral dissertation, Universitas Perintis Indonesia)., p. 2008.
Suhatri, Elfi, E. F. and Marsellinda, E. (2018) ‘Gambaran kadar elektrolit ( natrium dan kalium ) terapi gagal jantung di RSUP Dr . M . Djamil Padang’, Jurnal Sains Farmasi & Klinis, 5(3), pp. 243–246.
Tambuwun, C. F. D., Panda, A. L. and Rampengan, S. H. (2016) ‘Gambaran pasien gagal jantung dengan penyakit hipertensi yang menjalani rawat inap di RSUP Prof. Dr. R. D. Kandou Manado periode September – November 2016’, e-CliniC, 4(2). doi: 10.35790/ecl.4.2.2016.14680.
Tiara Yusan, R., Setyono, J. ., Kusuma, M. N. H., Wahyudin, W., Zainuddin, Z., & Nur, A. F. . (2021). Perbedaan Kesanggupan Kardiovaskular Pada Karyawan Pria Perokok Dan Non Perokok Di Fakultas Kedokteran Universitas Jenderal Soedirman. Healthy Tadulako Journal (Jurnal Kesehatan Tadulako), 7(3), 153-157. https://doi.org/10.22487/htj.v7i3.459
Wei, K. Y. et al. (2020) ‘Dietary potassium and the kidney: Lifesaving physiology’, Clinical Kidney Journal, 13(6), pp. 952–968. doi: 10.1093/CKJ/SFAA157.
Wulandari, T., Nurmainah and Robiyanto (2015) ‘Gambaran Penggunaan Obat Pada Pasien Gagal Jantung Kongestif Rawat Inap Di Rumah Sakit Sultan Syarif Mohamad Alkadrie Pontianak’, jurnal Farmasi Kalbar, 3(1), pp. 1–9.
Youssef, G. S. (2022) ‘Salt and hypertension: current views’, e-Journal of Cardiology Practice, 22(February), p. 2022.
Published
2024-03-30
How to Cite
ASWORO, Fadhillah Noor Izza; HEDININGSIH, Yekti; MARFUATI, Nanik.
HUBUNGAN KADAR NATRIUM DAN KALIUM SERUM DENGAN TEKANAN DARAH DAN DENYUT NADI PADA PASIEN GAGAL JANTUNG.
Mandala Of Health, [S.l.], v. 17, n. 1, p. 1-10, mar. 2024.
ISSN 2615-6954.
Available at: <http://jos.unsoed.ac.id/index.php/mandala/article/view/11470>. Date accessed: 29 apr. 2024.
doi: https://doi.org/10.20884/1.mandala.2024.17.1.11470.
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Articles
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