PERBEDAAN TINGKAT KEPARAHAN PSORIASIS PADA PASIEN PSORIASIS DENGAN DAN TANPA FOKAL INFEKSI

DIFFERENCE OF PSORIASIS AREA SEVERITY INDEX BETWEEN PATIENTS WITH AND WITHOUT FOCAL INFECTIONS

  • Caroline Astrid Fakultas Kedokteran, Universitas Jenderal Soedirman, Purwokerto, Indonesia
  • Ismiralda Oke Putranti Departemen Ilmu Kesehatan Kulit dan Kelamin, RSUD Prof. Dr. Margono Soekarjo, Purwokerto, Indonesia
  • Kurniasih Dwi Purwanti Klinik Psikologi, RSUD Dr. R. Goeteng Taroenadibrata, Purbalingga, Indonesia

Abstract

Psoriasis adalah penyakit kulit yang sering dijumpai, kronik, tidak menular, terjadi akibat kelainan kompleks pada pertumbuhan dan diferensiasi epidermal serta abnormalitas multipel dari biokimia, imunologi, dan vaskular. Salah satu faktor risiko psoriasis adalah fokal infeksi. Penelitian ini bertujuan mengetahui perbedaan tingkat keparahan psoriasis pada pasien psoriasis dengan dan tanpa disertai fokal infeksi di RSUD Prof. Dr. Margono Soekarjo, Purwokerto. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross-sectional. Subjek penelitian adalah 40 pasien psoriasis yang berobat di Poli Kulit dan Kelamin RSUD Prof. Dr. Margono Soekarjo pada bulan November hingga Desember 2017 yang memenuhi kriteria inklusi dan eksklusi. Tingkat keparahan psoriasis diukur menggunakan Psoriasis Area Severity Index (PASI). Analisis data menggunakan independent t-test. Rata-rata tingkat keparahan psoriasis pada pasien dengan fokal infeksi 28,63 dan tanpa fokal infeksi 17,29, dengan jenis fokal infeksi didapatkan fokal infeksi intraoral (47,5%) dan genital (2,5%). Perbedaan tingkat keparahan psoriasis pada pasien dengan dan tanpa fokal infeksi didapatkan p = 0,000 (p < 0,05). Terdapat perbedaan signifikan tingkat keparahan psoriasis pada pasien dengan dan tanpa fokal infeksi.


 


 


Psoriasis is a common, chronic, noncontagious skin disease, caused by complex abnormal epidermal growth with multiple abnormality of biochemistry, immunology, and vascular. One of psoriasis risk factors is focal infection. This study was an analytical study with cross-sectional approach, to establish the difference of Psoriasis Area Severity Index (PASI) in patients with and without focal infections in Prof. Dr. Margono Soekarjo Public Hospital, Purwokerto. Subjects of this study were psoriasis outpatients in Dermatology and Venereology Clinic in November until December 2017. Forty subjects who fulfilled the inclusion and exclusion criteria were measured using PASI. This study showed the average of the PASI on patients with focal infections was 28.63 and without focal infections was 17.29, with types of the focal infection were intraoral focal infections (47,5%) and genital focal infections (2,5%). The difference of PASI between patients with and without focal infections was significant with p = 0,000 (p < 0,05). There is a significant difference on degree of psoriasis between patients with and without focal infections.

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Published
2018-12-31
How to Cite
ASTRID, Caroline; PUTRANTI, Ismiralda Oke; PURWANTI, Kurniasih Dwi. PERBEDAAN TINGKAT KEPARAHAN PSORIASIS PADA PASIEN PSORIASIS DENGAN DAN TANPA FOKAL INFEKSI. Mandala Of Health : A Scientific Journal, [S.l.], v. 11, n. 2, p. 80-94, dec. 2018. ISSN 2615-6954. Available at: <http://jos.unsoed.ac.id/index.php/mandala/article/view/944>. Date accessed: 15 july 2020. doi: https://doi.org/10.20884/1.mandala health.2018.11.2.944.