COMPARISON THE DURATION OF SPUTUM CONVERSION IN NEW CASE SMEAR POSITIVE PULMONARY TUBERCULOSIS PATIENTS WITH AND WITHOUT DIABETES MELLITUS

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Radita Ikapratiwi Indah Rahmawati Joko Mulyanto

Abstract

Tuberculosis (TB) is considered as the leading killer among infectious diseases because of bacteria resulted in a high number ofmorbidity and mortality world wide. One risk factor for tuberculosisis diabetes mellitus (DM). The prevalence of TB and DM jump together globally, especially in developing countries, including Indonesia. Early and accurate diagnosis of TB cases in the enforcement is sputum smear examination. Monitoring of TB seen through sputum conversion. The purpose of this studyis to determine the duration of sputum conversion difference new case smear positive pulmonary TB patients with and without DM in hospital Prof. Dr.Margono Soekarjo (RSMS) Purwokerto. Thestudy design is observational analytic with cohort retrospective study. Sample of this study was patients who checked their health in Lung Clinis of RSMS Purwokerto obtained total sample of 44 people, consisting of 22 patients clinically diagnosed new cases smear-positive pulmonary TB with DM and 22 patients without DM in 2009 until 2012.Results of this study were analyzed using Fisher Exact Test. pvalues obtainedof 0.000 (p <0.05) (95% CI = 0,288-0,718) with relative risk 0,455. The conclusion is there were significant differences in sputum conversion time between the group of patients suffering from pulmonary uberculosis with and without DM. The conversion of sputum in patients with pulmonary tuberculosis who suffered DM is longer than patients without DM. Relative risk value which is equal to 0.455 which means that patients with DM have pulmonary tuberculosis risk by 0.455 times more likely to experience delays in sputum conversion than TB patients without DM

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IKAPRATIWI, Radita; RAHMAWATI, Indah; MULYANTO, Joko. COMPARISON THE DURATION OF SPUTUM CONVERSION IN NEW CASE SMEAR POSITIVE PULMONARY TUBERCULOSIS PATIENTS WITH AND WITHOUT DIABETES MELLITUS. Mandala Of Health : A Scientific Journal, [S.l.], v. 8, n. 1, p. 585 -594, oct. 2017. ISSN 2615-6954. Available at: <http://jos.unsoed.ac.id/index.php/mandala/article/view/347>. Date accessed: 18 july 2019. doi: https://doi.org/10.20884/1.mandala.2017.8.1.347.
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