NILAI DIAGNOSTIK USG COLOR DOPPLER DAN ELASTOGRAFI DIBANDINGKAN DENGAN HASIL BIOPSI ASPIRASI JARUM HALUS DALAM MENENTUKAN LIMFADENOPATI LEHER JINAK DAN GANAS

Abstract

Limfadenopati didefinisikan sebagai sebuah abnormalitas ukuran dan konsistensi dari limfonodus yang bisa terjadi akibat proses infeksi dan inflamasi lainnya. Penelitian ini bertujuan menjelaskan nilai diagnostik USG color Doppler dan Elastografi dalam menentukan limfadenopati leher jinak dan ganas dibandingkan dengan hasil Bajah. Penelitian ini dilaksanakan di Bagian Radiologi RS Universitas Hasanuddin, Makassar yang dimulai pada bulan Februari-Maret 2018. Desain penelitian menggunakan uji diagnostik. Sebanyak 50 sampel dengan klinis limfadenopati leher. Dilakukan pemeriksaan ultrasonografi color Doppler untuk melihat pola, lokasi vascular serta nilai resistive index, kemudian dilakukan elastografi untuk menentukan elastisitas jaringan. Dilanjutkan dengan melakukan pemeriksaan Bajah untuk menentukan limfadenopati leher jinak dan ganas sete. Analisis data menggunakan statistik melalui uji diagnostik. Hasil penelitian menunjukkan bahwa dari uji diagnostik, didapatkan pola vaskuler memiliki sensitivitas 72%, spesifitas 92%, akurasi 84%, NPP 88%, NPN 81%. Lokasi vaskuler memiliki sensitivitas 59%, spesifitas 86%, akurasi 80%, NPP 92%, NPN 75%. Nilai resistive indeks didapatkan cut 0ff 0,795 dengan nilai sensitivitas 95,5%, spesifitas 75%, akurasu 84%, NPP 75% dan NPN 95,5%. Apabila dibandingkan dengan USG color Doppler dan elastografi, maka elastografi jauh lebih unggul dalam menentukan limfadenopati leher jinak dan ganas dengan sensitivitas 95,4%, spesifitas 96,4%, akurasi 96%, nilai prediksi positif 95,4% dan nilai prediksi negatif 96,4%.

Lymphadenopathy is defined as an abnormality in the size and consistency of the lymph nodes that can occur due to other infections and inflammatory processes. This study aimed to determine the diagnostic value of ultrasound color Doppler and Elastography in determining the benign and malignant cervical lymphadenopathy compared with the results of the elephant Research method. This research was conducted in Radiology Department of Hasanuddin University Hospital, Makassar which started in February-March 2018. The research design used the diagnostic test. A total of 50 samples with clinical cervical lymphadenopathy. The color Doppler ultrasound examination was conducted to find out the pattern, vascular location and resistive index value, then the elastography was performed to determine the elasticity of the tissue. After that, a FNA examination was done to determine benign and malignant cervical lymphadenopathy. The data analysis used the statistic through the diagnostic tests. The research results indicated that the diagnostic test revealed the vascular pattern of 72% sensitivity, 92% specificity, 84% accuracy, NPP 88%, NPN 81%. The vascular site had a sensitivity of 59%, specificity 96%, accuracy of 80%, NPP of 92%, NPN of 75%. The resistive values index obtained 0ff 0.795 with 95.5% sensitivity, 75% specificity, 84% accuracy, 75% NPP, and 95.5% NPN. When compared with Doppler ultrasound and elastography, the elastography was superior in determining benign and malignant cervical lymphadenopathy with 95.4% sensitivity, 96.4% specificity, 96% accuracy, 95.4% NPP and NPN of 96.4 %. Thus, Doppler ultrasound and elastography had high diagnostic values, which could be used to determine both benign and malignant cervical lymphadenopathy.