• Alya Yasmin
  • Binta Febriana Zahra Setiawan Department of Nutrition, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto
  • Tutut Rizki Indriyani Department of Nutrition, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto
  • Saryono Saryono Department of Nursing, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto


Introduction: Omega-3 fatty acids are found in fish oil. Omega-3 fatty acids play a role in the primary and secondary prevention of cardiovascular disease. Cardiovascular disease (CVD) is the leading cause of death in both developed and developing countries. Cardiovascular is a disease group that includes coronary heart disease (CHD), cerebrovascular disease, peripheral artery disease, rheumatic heart disease, deep vein thrombosis, and pulmonary embolism. Purpose: This systematic review aims to identify the prevention of cardiovascular events using fish oil. Methods: This journal was obtained from the Google Scholar, Pubmed, and Science Direct databases, which then extracted the data by looking at all the selected publication articles.  Results: This reviewed journal shows the beneficial effects of fish oil in reducing mortality from cardiovascular disease. Omega-3s show benefits for preventing cardiovascular disease because omega-3s can reduce blood platelets and thus prevent the clogging of arteries. Discussion: Arterial blood vessels are at risk of obstructing blood flow to the heart. Conclusion: Thus, it can be concluded that fish oil can reduce the risk of cardiovascular disease.


Farahdika, Amalia and Azam, Mahalul. 2015. Risk Factors Associated with Coronary Heart Disease in Middle Adult (41-60 Years) (Case Study in Semarang City General Hospital). Department of Public Health 4 (2): 117-123
Fonda, Grace. 2016. Role of Omega-3 Fatty Acids in Dyslipidemia and Cardiovascular Diseases. Tangerang and Yogyakarta: Faculty of Medicine, University of Pelita Harapan and Faculty of Medicine, Gadjah Mada University. Journal of Indonesian Cardiology J Indonesian Cardiol. 2016; 37: 213-22 ISSN 0126/3773.
Guilherme, L. and Kalil, J. 2010. 'Rheumatic fever and rheumatic heart disease: Cellular mechanisms leading autoimmune reactivity and disease', Journal of Clinical Immunology, 30 (1), pp. 17–23. doi: 10.1007 / s10875-009-9332-6
Kris-Etherton, PM, Harris, WS, & Appel, LJ (2002). Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation, 106 (21), 2747–2757.
Kromhout, D., Yasuda, S., Geleijnse, JM, & Shimokawa, H. (2012). Fish oil and omega-3 fatty acids in cardiovascular disease: Do they really work? European Heart Journal, 33 (4), 436–443.
Lannywati, et al. 2016. Dominant risk factors of coronary heart disease in Indonesia. Jakarta: Center for Research and Development of Health Resources and Services. Health Research Bulletin, Vol. 44, No. 3, September 2016: 153 – 164.
Leaf, A., Albert, CM, Josephson, M., Steinhaus, D., Kluger, J., Kang, JX, Cox, B., Zhang, H., & Schoenfeld, D. (2005). Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake. Circulation, 112 (18), 2762–2768.
Lestari, et al. 2014. Risk Factors for Cardiovascular Disease (Study on Smoker Students, Faculty of Engineering, Department of Mechanical Engineering, Diponegoro University, Semarang). Semarang. Journal of Public Health. Vol.2, no.1.2014
Lin, Z., Chen, R., Jiang, Y., Xia, Y., Niu, Y., Wang, C., Liu, C., Chen, C., Ge, Y., Wang, W., Yin, G., Cai, J., Clement, V., Xu, X., Chen, B., Chen, H., & Kan, H. (2019). Cardiovascular Benefits of Fish-Oil Supplementation Against Fine Particulate Air Pollution in China. Journal of the American College of Cardiology, 73 (16), 2076–2085.
Maulana, Indra. 2014. The Content Of Fatty Acids In Indonesia's Fish Oil. Bandung: School of Pharmacy ITB. Journal of Tropical Marine Science and Technology, Vol. 6, No. 1, p. 121-130.
Nestel, PJ (2000). Fish oil and cardiovascular disease: Lipids and arterial function. American Journal of Clinical Nutrition, 71 (1 SUPPL.), 228–231.
Riskesdas, 2013, Basic Health Research, Health Research and Development Agency of the Ministry of Health of the Republic of Indonesia, Jakarta.
Salasah, Rosmawati. 2016. The Study of Increasing Epa and Dha Omega-3 Fatty Acids in Catfish Oil Feed with Soybean Oil. Postgraduate Agricultural Masters Study Program, Tadulako University.
Soeharto, 2001, Prevention and Cure of Coronary Heart Disease, Second Edition, Gramedia Pustaka Utama, Jakarta.
Weitz, D., Weintraub, H., Fisher, E., & Schwartzbard, AZ (2010). Fish oil for the treatment of cardiovascular disease. Cardiology in Review, 18 (5), 258–263.
World Health Organization, WHO. 2016. Global Health Observatory Data. Repository: heart disease-causes-of-death-highest-kemenkes-remind-ingenious. Retrieved March 15, 2021.
How to Cite
YASMIN, Alya et al. UTILIZATION OF FISH OIL TO REDUCE THE RISK OF CARDIOVASCULAR DISEASE. International Journal of Biomedical Nursing Review, [S.l.], v. 1, n. 1, p. 43-51, aug. 2022. Available at: <http://jos.unsoed.ac.id/index.php/ijbnr/article/view/6533>. Date accessed: 30 nov. 2022.